Does convalescent plasma work against COVID-19? Who knows? – Science-Based Medicine
Does convalescent plasma work against COVID-19? Who knows? – Science-Based Medicine
So what do we know about the use of convalescent plasma versus COVID-19? Sadly, the answer is: Not much. We have some small case series, such as this one of five critically ill patients, all of whom recovered, but they’re not that useful other than as preliminary studies. We have a small randomized clinical trial of 103 patients in Wuhan, China with severe or life-threatening COVID-19, which was a negative trial. That’s not surprising, though, given that plasma therapy is usually less effective or actually ineffective in advanced, severe disease.