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Picaridin vs DEET: Which Is the Best Insect Repellent?

"Created by Bayer in the 1980s, picaridin (pronounced pih-CARE-a-den) is a synthetic compound developed from a plant extract from the genus Piper, the same plant genus that produces table pepper. Picaridin has been available since 1998 in Europe and Australia—where it is the best-selling insect repellent—but was approved for sale in the United States only in 2005. (You may see it listed as KBR 3023, Bayrepel, or icaridin.) As with DEET, the EPA has concluded that the normal use of picaridin does not present a health concern."

"Studies have shown picaridin to be as effective as DEET in repelling mosquitoes. Unlike DEET, however, picaridin is odorless, non-greasy, and does not dissolve plastics or other synthetics. The one possible concern with picaridin is its relative newness. Insufficient time has passed for long-term health risks (should they exist) to manifest themselves. A limited, but growing, number of repellents contain picaridin, including Cutter Advanced, Sawyer Premium, and Repel Smart Spray."